2019 AIChE Annual Meeting

Session: Poster Session: Pharmaceutical

This poster session highlights academic and industrial research related to advancements in drug discovery, development, and manufacturing. Topics related to drug substance, drug product, and biopharmaceuticals are welcomed.

Chair

Changi, S. M., University of Michigan

Co-Chairs

Seymour, C., Pfizer
Tandogan, N., Eli Lilly & Co

Presentations

03:30 PM

(189q) Optimizing the Pharmaceutical Cleaning Process: Challenges and Opportunities
Mouras, R., Walker, G., Albadarin, A. B.
(189aa) Understanding Polymorphic Phase Transformations of Acetaminophen in Polymer-Based Formulation Processes
Hernández Espinell, J., Orta, B., López-Mejías, V., Stelzer, T., López Burgos, G.
(189r) The Development of a 2-Step Buprenorphine Intermediate 5 Process
Zhang, W. C.
(189k) In-Line NIR Spectroscopy for Monitoring the Preparation of Ginkgo Biloba Extract Solid Dispersions By Hot-Melt Extrusion
Liu, L., Qu, H.
(189ac) Development of a Blistering Packaging Process with Nitrogen-Modified Headspace
Dowst, M. R., Vandiver, J. M., Oliveira, M., Kodgule, N. S., Young, M., Tawa, M., Connolly, E.
(189g) Experimental Analysis of Influence Screw Configuration in View of Understanding Granulation Mechanism in Pharmaceutical Twin-Screw Melt Granulation
Van de Steene, S., De Beer, T., Vervaet, C., Van Renterghem, J.
(189o) Development of an Expanded Parametric PBE Using Experimental Data from a High Shear Wet Granulation Process
Candelaria, M., Torrens-Sotomayor, L. F., Velazquez, C.
(189ab) Application of Artificial Neural Network As a Predictive Tool for Continuous Liposome Processing
Sansare, S., Costa, A., Xu, X., Mohammadiarani, H., Cruz, C., Lee, S. L., Burgess, D., Chaudhuri, B.
(189p) A Chemical Engineering Approach to Modelling Drug Dissolution and Transport Phenomena in the Lower Gastrointestinal Tract
O'Farrell, C., Stamatopoulos, K., Simmons, M., Batchelor, H. K., Karlsson, E. M., Marciani, L., Sulaiman, S.
(189ae) Buckling of a Drying Colloidal Drop
Tirumkudulu, M.
(189d) Establishing Meaningful Alarm Limits for a Continuous Direct Compression Process
Brandon, J.
(189b) Advancing from QbD to Operational Excellence in Continuous Pharmaceutical Manufacturing
Reklaitis, G. V. R., Ganesh, S., Nagy, Z. K., Vo, L. B. D., Rentz, B.
(189i) Agitator Impact on the Net Weight Signal of a Loss-in-Weight Feeder Operating at Low Mass Flow Rates
O'Mahony, M., Dale, S., Dinarello, E., Connelly, G., Kinney, I., Gloria, H.
(189l) Filtration Studies Combined with Mechanistic Modelling to Reliable API Process Understanding and Scale-up
Pina Campos, R., Ataíde, F., Cruz, A., Leitão, E., Loureiro, R.
(189s) Arginine Interactions Resulting in Virus Inactivation
Meingast, C., Joshi, P. U., Heldt, C.
(189n) Forget Throughput, It’s about the Risk- Rethinking Dead-End Membrane Filtration Scale-up
Wei, K.
(189u) Characterization of the Formulation-Process Interaction for Improved Thermal Bonding in the Manufacture of a Novel Ultra-Long Acting Oral Dosage Form
Holar, S., Dufour, D., Low, S., Grant, T., Sykes, K., Kanasty, R., Jaramillo Montezco, J.
(189v) Development of pH -Responsive Disintegrating Matrices for Safe Intestinal Transit of Gastric Resident Dosage Forms
Jaramillo Montezco, J., Holar, S., Sykes, K., Kanasty, R., Grant, T., Schwarz, M., Low, S., Yang, J., Bellinger, A., Alteruter, D.
(189t) Once Weekly Oral Ivermectin for Prevention of Malaria Transmission in Zone IVb
Yang, J., Kanasty, R., Grant, T., Holar, S., Jaramillo Montezco, J., Biswas, D., Habshey, A., Low, S.
(189c) Application of Life-Cycle Concepts in Drug Substance Manufacturing
Pazhayattil, A. B., Ingram, M.
(189h) How a Material Property Library Can Promote Rapid Process Development
Scicolone, J., Muzzio, F. J.
(189j) Temperature Mapping of Pharmaceutical Trickle Bed Reactor for Continuous Hydrogenation
Sheng, H., Pfisterer, D., Ljubicic, T., Hawkins, J., Mustakis, J., Diaz, A.
(189a) A Comprehensive Sensitivity Analysis for Risk Assessment of a Pharmaceutical Crystallization Process
Öner, M., Stocks, S. M., Abildskov, J., Sin, G.
(189w) Single-Use Centrifuge for Large Scale Separation and Collection of CHO and mAbs, and Other Cell Culture Applications
Richardson, D.
(189x) Solubility Enhancement of Hydrophobic Drug Molecules Via Amorphous Solid Dispersions and Flash Nanoprecipitation
Caggiano, N., Prud'homme, R. K., Priestley, R. D.
(189z) Enhancing the Long-Term Storage Stability of Amorphous Drug-Polyelectrolyte Nanoparticle Complex Via Incorporation of Hypromellose
Hadinoto, K., Chew, J. W.
(189e) Assessment of Blend Uniformity in a Continuous Tablet Manufacturing Process
Sierra-Vega, N. O., Méndez-Román, R.
(189ad) Dropwise Additive Manufacturing for Pharmaceuticals
Radcliffe, A. J., Nagy, Z. K., Reklaitis, G. V. R.
(189f) Continuous Pharmaceutical Manufacturing of Uniform Crystals in Slug Flow
Mou, M., Li, H., Yang, B. S., Jiang, M.
(189y) Comparison of Oral Drug Dissolution between Medium and Long Chain Unsaturated and Saturated Triglycerides: A Modeling-Based Approach
Singh, B.
(189m) Filtration Process Modeling and Scale-up for Robust Drug Substance Manufacturing
Hu, W., Orihuela, C., Fogle, J.