2019 AIChE Annual Meeting

Session: Modeling and Control of Crystallization I

This session focuses on the control of crystallization process and the development of crystallization processes using modeling.

Chair

Zoltan K. Nagy, Purdue University

Co-Chair

Michael Lovette, Amgen Inc.

Presentations

08:03 AM

(284a) Crystallization Kinetics of Cephalexin in the Presence of Cephalexin Precursors
Matthew McDonald, Andy Bommarius, Martha Grover, Ronald Rousseau

08:24 AM

(284b) Towards Enhanced Understanding of Sono-Crystallization for Pharmaceuticals
Daniel Pohlman, Moussa Boukerche, Jie Chen, Nandkishor Nere

08:45 AM

(284c) Technoeconomic MINLP Optimisation of M.S.M.P.R. Cascades for Continuous Crystallisation of Melitracen Hydrochloride, an Antidepressant API
Samir Diab, Dimitrios Gerogiorgis

09:06 AM

(284d) Controlled Manipulation of the Size and Shape of Needle-like Crystals in a Cyclic Process
Stefan Boetschi, Ashwin Kumar Rajagopalan, Manfred Morari, Marco Mazzotti

09:27 AM

(284e) Digital Design and Operation of Continuous Crystallization Processes Via Mechanistic Modelling
Niall Mitchell, John Mack, Furqan Tahir, Cameron Brown, Tariq Islam, John Robertson, Eduardo Lopez-Montero, Alastair J. Florence

09:48 AM

(284f) Quality By Control (QbC) Guided Quality By Design (QbD) for the Optimal Operation of Integrated Crystallizer-Wet Mill Systems
Zoltan K. Nagy, Botond Szilagyi