2019 AIChE Annual Meeting

Session: Innovations and Emerging Technologies: Drug Substance and Drug Product Development

This session highlights recent innovations and emerging technologies related to drug substance and drug product development. The focus is on development and implementation of novel techniques and processes, as relevant to unique challenges faced in drug substance/drug product and small/large molecules.

Chair

Lee, B. W., GlaxoSmithKline

Co-Chair

Azad, M., North Carolina A&T State University

Presentations

03:30 PM

(410a) Formulating Biologics in Polymeric Nanoparticles: New Methods to Overcome Manufacturing Barriers
Markwalter, C. E., Prud'homme, R. K., Pagels, R. F.

03:51 PM

(410b) Co-Immobilization of Enzyme Cascades Enables One-Pot Industrial Immobilized Biocatalysis
Forstater, J. H., Bade, R., Grosser, S. T., An, C., Kolev, J. N., Robaire, S. A.

04:12 PM

(410c) Application of Membrane Technology for Metal Removal from a Reaction Mixture
Kelkar, M., Rasmussen, M., Hartung, J., Patel, H., Franczyk, T., Manjrekar, O., Zhang, G., Chaaya, E., Nere, N.

04:33 PM

(410d) Applications of Soft Sensors in Pharmaceutical Manufacturing Processes
Wang, Z., Kamyar, R., Mehdizadeh, H.

04:54 PM

(410e) Process Performance of a Novel Continuous Process Line for Drying of an Active Pharmaceutical Ingredient
Aigner, I., Zettl, M., Krumme, M., Mannschott, T., van der Wel, P., Khinast, J. G.

05:15 PM

(410f) On-Demand Drug Product Manufacturing in a Miniaturized System: Can Formulation be Simplified?
Azad, M., Osorio, J. G., Wang, A., Klee, D., Eccles, M., Grela, E., Sloan, R., Hammersmith, G., Rapp, K., Brancazio, D., Myerson, A.

05:36 PM

(410g) Slow Freezing Process Design for Human Induced Pluripotent Stem Cells By Modeling Intracontainer Variation
Hayashi, Y., Horiguchi, I., Kino-oka, M., Sugiyama, H.