2019 AIChE Annual Meeting

Session: Innovations and Emerging Technologies: Drug Substance and Drug Product Development

This session highlights recent innovations and emerging technologies related to drug substance and drug product development. The focus is on development and implementation of novel techniques and processes, as relevant to unique challenges faced in drug substance/drug product and small/large molecules.

Chair

Boung Wook Lee, GlaxoSmithKline

Co-Chair

Mohammad Azad, North Carolina A&T State University

Presentations

03:30 PM

(410a) Formulating Biologics in Polymeric Nanoparticles: New Methods to Overcome Manufacturing Barriers
Chester E. Markwalter, Robert K. Prud'homme, Robert F Pagels

03:51 PM

(410b) Co-Immobilization of Enzyme Cascades Enables One-Pot Industrial Immobilized Biocatalysis
Jacob H. Forstater, Rachel Bade, Shane T. Grosser, Chihui An, Joshua N. Kolev, Sandra A. Robaire

04:12 PM

(410c) Application of Membrane Technology for Metal Removal from a Reaction Mixture
Manish Kelkar, Mike Rasmussen, John Hartung, Harsit Patel, Thaddeus Franczyk, Onkar Manjrekar, Geran Zhang, Elie Chaaya, Nandkishor Nere

04:33 PM

(410d) Applications of Soft Sensors in Pharmaceutical Manufacturing Processes
Zilong Wang, Reza Kamyar, Hamidreza Mehdizadeh

04:54 PM

(410e) Process Performance of a Novel Continuous Process Line for Drying of an Active Pharmaceutical Ingredient
Isabella Aigner, Manuel Zettl, Markus Krumme, Thomas Mannschott, Peter van der Wel, Johannes G. Khinast

05:15 PM

(410f) On-Demand Drug Product Manufacturing in a Miniaturized System: Can Formulation be Simplified?
Mohammad Azad, Juan G. Osorio, Allison Wang, David Klee, Mary Eccles, Erin Grela, Rebecca Sloan, Gregory Hammersmith, Kersten Rapp, David Brancazio, Allan Myerson

05:36 PM

(410g) Slow Freezing Process Design for Human Induced Pluripotent Stem Cells By Modeling Intracontainer Variation
Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama