2019 AIChE Annual Meeting

Session: Computational Approaches to Protein Engineering

This session focuses on the evaluation and implementation of computational approaches to protein engineering. Relevant topics include new biophysical analyses, computational tools, and innovative approaches for navigating complex, multi-component biomolecular landscapes. Presentations addressing new challenges in protein engineering are particularly encouraged.

Chair

Yongku Cho, University of Connecticut

Co-Chairs

Jerome M. Fox, University of Colorado, Boulder
Brad Bundy, Brigham Young University

Presentations

12:30 PM

(681a) A Novel Interaction-Oriented Approach for Predicting Off-Target Antibody Specificities
Varun Chauhan, Robert Pantazes

12:48 PM

(681b) Developing Similarity Matrices for Protein-Protein Interactions
Robert Pantazes, Sumaiya Islam

01:06 PM

(681c) Quantitative Characterization of Protein-Ligand and Protein-Protein Binding Processes Involved in Plant Hormone Signaling
Chuankai Zhao, Jiming Chen, Faisal Aldukhi, Alexander Moffett, Diwakar Shukla

01:24 PM

(681d) Ipro+/- Computational Protein Design Tool for Predicting Indels Along with Substitutions for Redesign of Channel Proteins and Enzymes Alike
Ratul Chowdhury, Costas Maranas

01:42 PM

(681e) Computational Protein Design Targeting Oxidized RNA Modifications
Asuka A. Orr, Juan Camilo Gonzalez Rivera, Sean M. Engels, Joseph M. Jakubowski, Brendan C. Woodcock, Lydia Contreras, Phanourios Tamamis

02:00 PM

(681f) Paired Simulations and Experimental Investigations into the Calcium-Dependent Bioactivity of Albumin
Dharmeshkumar Patel, Jagdish Suresh Patel, Stephanie Haag, F. Marty Ytreberg, Matthew Bernards

02:18 PM

(681g) Designing Protein Structures and Complexes with the Molecular Modeling Program Rosetta
Brian Kuhlman