2019 AIChE Annual Meeting

Session: Biomedical Applications of Protein Engineering

This session invites presentations focusing on biomedical applications of protein science and engineering. The topics include, but not limited to, antibody engineering, protein-protein interactions, amyloid aggregation, anti-microbial proteins and drug delivery.

Co-Chairs

Jin Ryoun Kim, New York University
Kevin Metcalf, University of California, San Francisco
Robert Pantazes, Auburn University

Presentations

08:00 AM

(627a) Engineering Multi-Epitopic Antibodies for Receptor Downregulation
Rakeeb Kureshi, Seth Ludwig, Jamie Spangler

08:18 AM

(627b) Phi – a Parameter for Quantifying the Specificity of Post-Translational Modification Site Targeting Antibodies
Yongku Cho, Dan Li

08:36 AM

(627c) Engineering a Blue Light Inducible Spycatcher System (BLISS) As a Tool for Protein Photo-Patterning and Optogenetics
Emily Hartzell, Justin Terr, Wilfred Chen

08:54 AM

(627d) Amyloid Aggregation of Bacillus Circulans Xylanase Under Native Conditions and Its Modulation By ?-Amyloid-Derived Peptide Fragments
Jin Ryoun Kim, Timothy Charlton, Vandan Shah, Tonianna Lynch, Jason Candreva, Edward Chau, Yanxi Yang, Hyunjoo Kim, Amy Wood

09:12 AM

(627e) Optimizing Cell-Free Protein Synthesis for Increased Yield, Solubility and Activity of Antimicrobial Protein Colicins
Xing Jin, Weston Kightlinger, Seok Hoon Hong

09:30 AM

(627f) Doxycycline Dependent Self-Inactivation of CRISPR-SpCas9 to Temporally Regulate on- and Off-Target Editing
Anju Kelkar, Yuqi Zhu, Theodore Groth, Gino Stolfa, Aimee Stablewski, Michael Nemeth, Naina Singhi, Sriram Neelamegham

09:48 AM

(627g) A Platform Technology for Dynamic Control of Cell Behavior
Laura Segatori