2018 AIChE Annual Meeting

Session: Mixing Scale-up/Scale-down Issues in Pharmaceutical and Biopharmaceuticals Processes

Mixing Issues and Scale-up/Scale-Down Strategies for the Production of Pharmaceutical and Biopharmaceuticals

Chair

Piero Armenante, New Jersey Institute of Technology

Co-Chair

Justin Walker, The Dow Chemical Company

Presentations

08:00 AM

(466a) Hydrodynamics Characteristics of a Stirred Tank Provided with Angle-Mounted Impellers Using Computational and Experimental Approaches
Piero Armenante, Chadakarn Sirasitthichoke, Ji Ma

08:30 AM

(466b) Experimental and CFD Study of Mixing Two Fluids of Different Properties and Its Application in Biological Drug Product Manufacture
Wei Chen, Weixian Shi, Rushikesh Patel, Christoph Bernoulli, Jasmine Rowe, Melissa Bentley, Nobel Vale, Dimuthu A. Jayawickrama

09:30 AM

(466d) Mini Continuous Stirred Tank Reactors (mini-CSTR) for Cell and Tissue Culture Applications
Salvador Gallegos Martínez, Christian Carlos Mendoza Buenrostro, Pamela I. Rellstab-Sanchez, Ricardo Hernández Medina, Ingrid Anaya Morales, Mohamadmahdi Samandari, Everardo Gonzalez Gonzalez, Andrés García Rubio, Ciro Angel Rodríguez-González, Grissel Trujillo-de Santiago, Mario Moisés Alvarez

10:00 AM

(466e) Power Dissipation and Power Numbers for a Retreat-Blade Impeller in Pharmaceutical Mixing Tanks and Reactors Using an Experimentally Validated Computational Approach
Piero Armenante, Adam J. Bindas, Chadakarn Sirasitthichoke