2018 AIChE Annual Meeting

Session: Enabling Technologies for Immunotherapy Development

This session will focus on technologies that support the development of novel immunotherapies. Topics of interest include but are not limited to genome editing in primary immune cells, in vivo imaging, and high-throughput protein engineering for immunotherapy applications.

Chair

Arnab Mukherjee, University of California Santa Barbara

Presentations

08:00 AM

(454a) Eradication of Primary and Cancer Stem Cells By Chemically Self-Assembled Nanoring Targeted T-Cells
Carston R. Wagner, Jacob R. Petersburg, Clifford M. Csizmar

08:18 AM

(454b) Inhibition of Peanut Induced Mast Cell Degranulation By Designing Covalent Heterobivalent Inhibitors
Jaeho Shin, Peter Deak, Baksun Kim, Tanyel Kiziltepe, Basar Bilgicer, Amina Abdul Qayum, Girish Vitalpur, Kirsten Kloepfer, Mark Kaplan

08:36 AM

(454c) Remote Control of Engineered T Cells Using Photothermal Pulses
Gabriel Kwong, Ian Miller, Marielena Gamboa Castro, Lee-Kai Sun, Jason Weis

08:54 AM

(454d) Serum Antibody Profiling of Nivolumab/Azacytidine-Treated Acute Myeloid Leukemia Patients Via High-Throughput Sequencing of Peptide Phage-Display Library
Jay R Adolacion, Navin Varadarajan, Richard C. Willson

09:19 AM

(454e) Yeast Surface Display Techniques Enhance Development of Chimeric Antigen Receptors for Hematologic Malignancies
Lawrence A. Stern, Laura Lim, Christian Huynh, Marissa M. Del Real, Lindsay O'Brien, Wen-Chung Chang, Michalina Silva, Brenda Aguilar, John C. Williams, L. Elizabeth Budde, Xiuli Wang, Christine E. Brown, Stephen J. Forman

09:37 AM

(454f) Efficient Incorporation of Matrix Protein M2 into Influenza Virus-like Particles (VLPs) for Improved Vaccine Manufacturing and Efficacy
Andrew Zak, Brett Hill, Syed Rizvi, Fei Wen

09:55 AM

(454g) Cytokine-like Regulation of T-Cell Fate Mediated By Tryptophan-Derived Microbiota Metabolites
Arul Jayaraman