2018 AIChE Annual Meeting

Session: Biomolecular Engineering

This session invites contributions on novel methods for engineering biomolecules and the applications of these in therapeutics, diagnostics, sensors, and other engineering applications. Novel in vitro and in vivo molecular engineering approaches are also encouraged. Fundamental experimental and computational studies on the structure and structure-function properties of engineered biomolecules are also welcome.

Co-Chairs

Kevin Cash, Colorado School of Mines - CBE
Mehmet A. Orman, Rutgers, The State University of New Jersey

Presentations

12:30 PM

(320a) Roles of Variable Linker Length in Dual Acting Virucidal Entry Inhibitors on HIV-1 Potency Via on-the-Fly Free Energy Molecular Simulations
Steven T. Gossert, Bibek Parajuli, Irwin Chaiken, Cameron F. Abrams

12:48 PM

(320b) Engineering Ligand-Activated Fusogens from Influenza Hemagglutinin
Mauricio Valverde, Marti Tooley, Eric T. Boder

01:06 PM

(320c) Site-Specific Immobilization and Orientation Control of Scfv-Fc Antibodies for Ultra-Sensitive Detection of Influenza Virus
Yoichi Kumada, Jun-ichi Horiuchi, Koichi Takahashi, Natsumi Kamiyoshi, Shinya Ogasawara, Fumio Gondaira

01:24 PM

(320d) Evolution-Guided Design of Phosphatase Inhibitors
Michael Hjortness, Laura Riccardi, Akarawin Hongdusit, Alex Ruppe, Mengxia Zhao, Edward Y. Kim, Peter H. Zwart, Banumathi Sankaran, Haribabu Arthanari, Marcelo Sousa, Marco De Vivo, Jerome M. Fox

01:42 PM

(320e) Improving Aptamer Specificity with Stringent Counterselection Methods
Jonah Rosch, Franklin Gong, Daniel Balikov, Ethan Lippmann

02:00 PM

(320f) Viable but Non-Culturable and Persistence Describe the Same Bacterial Stress State
Thomas K. Wood, Jun-Seob Kim, Nityananda Chowdhury, Ryota Yamasaki

02:18 PM

(320g) Invited Speaker: Bio-Nanomanufacturing of Protein Therapeutics Using Biomembrane Microfluidics
Susan Daniel