2018 AIChE Annual Meeting
(66c) Examining chitosan-titanium bonding with various addition in heated simulated body fluid
Authors
McWhorter, P. - Presenter, Youngstown State University
Martin, H. J., Youngstown State University
The bioactive coating, chitosan, bonded to titanium is one option to both reduce post-operation infections and improve the osseointegration of implants. Chitosan, which is a biopolymer, has been successfully bonded to titanium through the use of the linker molecule, aminopropyltriethoxysilane (APTES), deposited using heptane. Successful bonding of the chitosan polymer to titanium has occurred but different environmental effects or the long term behavior of the coating adhesion have not been examined. Determining how the chitosan-metal bond behaves in simulated body fluid maintained at body temperature over extended periods of time is vital in the use of the chitosan coated titanium. In addition, embedding hydroxyapatite to further increase osseointegration and gentamycin to further reduce infections can affect the behavior of the chitosan-metal bond. The research presented here will detail the adhesion behavior of chitosan-metal bond exposed to heated simulated body fluid over an extended period of time, as compared to atmospheric exposure, and how various additions to the chitosan coating affect the adhesion strength of the chitosan-metal bond.