2017 Annual Meeting

Session: Protein Engineering I: Therapeutics

This session will focus on engineering polypeptides for therapeutic applications. Topics of interest include, but are not limited to, selective cell targeting, imaging, and disruption of biological processes that contribute to disease.

Chair

Benjamin J. Hackel, University of Minnesota

Co-Chair

James Van Deventer, Tufts University

Presentations

08:00 AM

(504a) Engineering and Profiling the Substrate Specificity of Human Proteases for Therapeutic Applications
Carl A. Denard, Brent L. Iverson, Rasha Yaghi

08:18 AM

(504b) A Novel Transthyretin Peptide Mimic As a Therapeutic for Alzheimer’s Disease
Kayla Pate, Regina M. Murphy

08:36 AM

(504c) Directing Reversible Cell-Cell Interactions with Evolved Fibronectin Domains
Clifford M. Csizmar, Lawrence A. Stern, Jacob R. Petersburg, Benjamin J. Hackel, Carston R. Wagner

08:54 AM

(191ci) Design of a Cholesterol-Binding Peptide to Inhibit Bacterial Toxin Activity
Evan Koufos, Angela Brown

09:12 AM

(504e) Enhancing the Chemical Versatility of Yeast Display to Target the Tumor Microenvironment
James Van Deventer, Jessica T. Stieglitz, Haixing P. Kehoe, Gregory I. Berumen, Hanan Z. Lane, Laura B. Quinto

09:30 AM

(504f) Tunable Thermal Bioswitches for in vivo Control of Biological Therapeutics
Dan Piraner, Mohamad Abedi, Brittany Moser, Audrey Lee-Gosselin, Mikhail Shapiro

09:48 AM

(504g) Now You See Me, Now You Don’T—Building Better Biologics through Immune Evasion
Karl E. Griswold