2017 Annual Meeting

Session: Green Pharmaceutical Process Development and Biocatalysis

The session illustrates status and progress in the design of processes for pharmaceuticals that incorporate the concepts of Green Chemistry or of biocatalysis. Thus, contributions are highly encouraged to include Green Chemistry concepts and results, especially those that are backed up with quantitative metrics, or to include one or more biocatalytic steps.

Chair

Andy Bommarius, Georgia Institute of Technology

Co-Chair

Shane T. Grosser, Merck & Co. Inc.

Presentations

03:30 PM

(26a) Developing Improved Enzymes for Industrial Biocatalysis
Iman Farasat

03:55 PM

(26b) Technoeconomic Optimisation, Antisolvent Selection and Comparative Environmental Evaluation for Continuous Paracetamol Crystallisation
Hikaru G. Jolliffe, Dimitrios Gerogiorgis

04:20 PM

(26c) Metric-Driven Process Development of a Late Stage Drug Substance
Kathleen Lauser, Nathan Domagalski, Michaël Fenster, Max A. Mellmer, Thomas La Cruz, Eric M. Saurer, Matthew Winston

04:45 PM

(26d) Scalable Continuous Synthesis of Enantiomerically Pure Amine APIs in an Enzyme Membrane Reactor
Andy Bommarius, Robert D. Franklin, Bettina Bommarius

05:10 PM

(26e) Development of a Biocatalytic Cascade for the Deracimization of a Racemic Alcohol
Shane T. Grosser

05:35 PM

(26f) Design of New Reactors to Produce Levan Biopolymer through Enzymatic Catalysis: Kinetics and Mass Transfer
Álvaro González-Garcinuño, Alvaro Sanchez, Sonia Ruiz, Antonio Tabernero, Miguel A. Galan, Montaña Elviro, Antonio Monzón, Eva Martín del Valle