2017 Annual Meeting

Session: Development of Processes and Products for Pharmaceuticals and Hybrid Therapeutics

The session will include presentations that describe tools, technologies and applications related to the development of pharmaceutical products. Applications in both small molecules and biopharmaceuticals are welcome.

Chair

Co-Chair

Christopher L. Burcham, Eli Lilly and Company

Presentations

03:15 PM

(596a) Engineering Considerations for Dissolved Oxygen Sensor Response Across Silicone Membranes in 3-L Single Use Bioreactors
William Tran, John Bowers, T. Craig Seamans

03:36 PM

(596b) Process Development Tool to Rapidly Predict the Stability of Biopharmaceuticals
Sarah Hedberg, Yolanda Hutabarat, Jerry Heng, Jonathan Haigh, Daryl Williams

03:57 PM

(596c) Model-Based Process Optimization for Upstream Bioreactor Production–Downstream Chromatographic Separation of CHO Cell Monoclonal Antibodies (mAb)
Uroš Novak, Drejc Kopa?, Blaž Likozar, Andrej Pohar, Matic Grom, Miša Cajnko

04:18 PM

(596d) Exploring the Multi-Minima Behavior of Organic Crystal Polymorphs at Finite-Temperature
Eric Dybeck, Michael Shirts

04:39 PM

(596e) Iterative Synthesis of Heteropolymers Using Organic Solvent Nanofiltration
Ruiyi Liu, Piers Gaffney, Patrizia Marchetti, Andrew G. Livingston, Marc Schaepertoens, Ruijiao Dong

05:00 PM

(596f) Challenges in Process Development of Antibody Drug Conjugates (ADCs)
Vimalkumar Patel

05:21 PM

(596g) Improved Manufacturing Process for Semi-Synthetic Calicheamicin Linker-Payload En Route to Antibody-Drug Conjugates
Leo J. Letendre, Vimalkumar Patel, Frank W. Kotch, Amarnauth Prashad, Wesley Swanson, Xi Hu, Lawrence Chen, April Xu, Sen Zhang, Stephen Freese, Eric Bortell