2017 Annual Meeting

Session: Development of Processes and Products for Pharmaceuticals and Hybrid Therapeutics

The session will include presentations that describe tools, technologies and applications related to the development of pharmaceutical products. Applications in both small molecules and biopharmaceuticals are welcome.

Chair

Co-Chair

Burcham, C. L., Eli Lilly and Company

Presentations

03:15 PM

(596a) Engineering Considerations for Dissolved Oxygen Sensor Response Across Silicone Membranes in 3-L Single Use Bioreactors
Tran, W., Bowers, J., Seamans, T. C.

03:36 PM

(596b) Process Development Tool to Rapidly Predict the Stability of Biopharmaceuticals
Hedberg, S., Hutabarat, Y., Heng, J., Haigh, J., Williams, D.

03:57 PM

(596c) Model-Based Process Optimization for Upstream Bioreactor Production–Downstream Chromatographic Separation of CHO Cell Monoclonal Antibodies (mAb)
Novak, U., Kopa?, D., Likozar, B., Pohar, A., Grom, M., Cajnko, M.

04:18 PM

(596d) Exploring the Multi-Minima Behavior of Organic Crystal Polymorphs at Finite-Temperature
Dybeck, E., Shirts, M.

04:39 PM

(596e) Iterative Synthesis of Heteropolymers Using Organic Solvent Nanofiltration
Liu, R., Gaffney, P., Marchetti, P., Livingston, A. G., Schaepertoens, M., Dong, R.

05:00 PM

(596f) Challenges in Process Development of Antibody Drug Conjugates (ADCs)
Patel, V.

05:21 PM

(596g) Improved Manufacturing Process for Semi-Synthetic Calicheamicin Linker-Payload En Route to Antibody-Drug Conjugates
Letendre, L. J., Patel, V., Kotch, F. W., Prashad, A., Swanson, W., Hu, X., Chen, L., Xu, A., Zhang, S., Freese, S., Bortell, E.