Session: Model Based Integrated Design of Pharmaceutical Drug Substance Processes

This session seeks contributions showcasing the development and implementation of first-principles as well as data-driven process modeling, simulation and optimization methods for design and development of pharmaceutical processes for the production of key intermediates and APIs. Modeling approaches including CFD, DEM, FEM, PBM, Monte Carlo and other methods, or a focus on thermodynamic, kinetic and transport parameter estimation, are welcome. Authors are encouraged to highlight Quality by Design (QbD) mapping approaches, process integration and intensification achievements, process economics and environmental impact analyses.