2016 AIChE Annual Meeting

Session: Mixing Scale-Up/Scale-Down Issues in Pharmaceutical and Biopharmaceuticals Processes

Mixing Issues and Scale-up/Scale-Down Strategies for the Production of Pharmaceutical and Biopharmaceuticals

Chair

Piero M. Armenante, New Jersey Institute of Technology

Co-Chairs

Luis Sierra, Merck Sharp & Dohme
Amanda M. Lewis, The University of Texas at Austin

Presentations

08:30 AM

(487a) Evaluating Mixing Performance in a Stirred Tank Reactor with Different Impeller Geometries and Reactor Size By CFD
Rui C. Silva, Jose Luis Santos, Filipe A.P. Ataíde

08:52 AM

(487b) CFD Simulation on Assessment of Biologic Product Mixing Performance in Single Use Technology
Chris Lee, Wei Chen, Rao Mantri, Howard Stamato

09:14 AM

(487c) Characterization of Lab and Plant Reactors Using Fast Competitive Reactions and a Predictive Model
Joe Hannon, Andrew Bird, Andrew Derrick

09:36 AM

(487d) Computational and Experimental Determination of the Hydrodynamics in a Scaled-Down Pharmaceutical Vessel Provided with Angle-Mounted Impellers
Ji Ma, Piero M. Armenante

09:58 AM

(487e) Experimental Study of Wet Milling in a Rotor-Stator Mixer
Richard Calabrese, Kanan Ghaderzadeh

10:20 AM

(487f) Practical Large Eddy Simulation
John A. Thomas, Kevin Smith

10:42 AM

(487g) Scale-up Rules for the Generation of Solid-Stabilized Emulsions
Louis Fradette, Emir Tsabet, Alexandre Al-Haiek