2015 AIChE Annual Meeting Proceedings

Session: Synthetic and Systems Biology in Human Health

This session will cover tools and applications geared towards using synthetic and systems biology to solve problems in human health. Areas include but are not limited to the study and engineering of microbiomes, antibiotic resistance, immunology, cell metabolism, and cell-based diagnostics and therapeutics. Speakers from both academia and industry are encouraged to present in this session.

Chair

Yvonne Chen, University of California, Los Angeles

Co-Chair

Deepak Nagrath, Rice University

Presentations

12:30 PM

(559a) Chemical-Genetic Inference of Antibiotic Interactions for Combination Therapies
Sriram Chandrasekaran, James J Collins, Murat Cokol

12:48 PM

(559b) Dissecting the Effects of (5Z)-4-Bromo-5-(bromomethylene)-3-Butyl-2-(5H)-Furanone on Bacillus Anthracis Metabolism
Christine Endicott, Ranjan Srivastava

01:06 PM

(559c) Discovery and Dissection of Metabolic Oscillations in the Nitric Oxide Response of Escherichia coli Under Microaerobiosis
Jonathan L. Robinson, Mark Brynildsen

01:24 PM

(559d) Identification of Gut Microbiota-Derived Metabolites As Liver Inflammation Modulators in Non-Alcoholic Fatty Liver Disease
Smitha Krishnan, Kyongbum Lee, Arul Jayaraman, Maria Choi, Nima Saedi, Yufang Ding, Martin L. Yarmush

01:48 PM

(559e) Identifying Motifs Associated with Autoimmune Diseases Using Next Generation Sequencing Experiments
Robert J. Pantazes, Patrick Daugherty

02:06 PM

(559f) Novel Approach to Target Endogenous KRAS Mutations By the Crispr/Cas9 Technology
Kristina Ehrhardt, Yi Li, Neha Kashyap, Michael White, Saurabh Mendiratta, Leonidas Bleris

02:24 PM

(559g) Rewiring Cellular Input-Output to Engineer Cell-Based Therapies That Interface Robustly with Human Physiology
Kelly A. Schwarz, Joshua N. Leonard, Rachel M. Dudek, Nichole Daringer

02:42 PM

(559h) Understanding Tumor Microenvironment's Metabolic Regulation of Cancer Cells
Deepak Nagrath, Lifeng Yang