2014 AIChE Annual Meeting

Session: Interfacial Phenomena in Pharmaceuticals

This session will address the role of interfacial phenomena in drug development and processing. Topics may include, but are not limited to: physicochemical interactions between drug products and interfaces / surfaces, mass transport to / from an interface, surfactant effects, shear effects on stability, and crystallization of drug product.

Chair

Dhar, P., University of Kansas

Co-Chair

Kastantin, M. J., University of Colorado

Presentations

08:30 AM

Welcoming Remarks

08:35 AM

(753a) Liquid Chromatography at the Single-Molecule Level
Mabry, J. N., Skaug, M. J., Schwartz, D. K.

08:55 AM

(753b) Water-Soluble Drug Partitioning and Adsorption in Polyelectrolyte Hydrogels
Dursch, T. J., Taylor, N. O., Liu, D. E., Prausnitz, J. M., Radke, C. J.

09:15 AM

(753c) Transport of Drugs Across Surfactant Covered Emulsion Interfaces
Chauhan, A., Damitz, R. A.

09:35 AM

(753d) Protein Aggregation Dynamics at the Silicone Oil/Water Interface of Model Proteins Using Single-Molecule TIRF Microscopy and Dynamic Interfacial Tensiometry
McUmber, A. C., Randolph, T. W., Schwartz, D. K.

09:55 AM

(753e) Monitoring Adsorption and Aggregation of an Intrinsically Disordered Protein at Solid Substrates
Mucci, N., Gamblin, T. C., Dhar, P.

10:15 AM

(753f) Stability of Monoclonal Antibody Solutions Subject to Expansion/Compression Cycles at the Air/Water Interface
Fuller, G., Pathak, J. A., Lin, G.

10:35 AM

(753g) Interactions of Bare and Protein-Loaded Adjuvants with Model Lipid Raft Mixtures at Model Interfaces
Dhar, P., Berkland, C., Antunez, L.

10:55 AM

Concluding Remarks