2014 AIChE Annual Meeting

Session: Computational Systems Biology in Biopharmaceutical Development

This session will highlight the application of computational and systems biology approach in biopharmaceutical development. Papers integrating mathematical modeling, experimental measurement, and data analysis, as well as innovative biopharmaceuticals or new therapy will be encouraged.

Chair

Lufang Zhou, The University of Alabama at Birmingham

Co-Chair

Presentations

12:30 PM

(494a) Robust Parameter Estimation for Physiologically Based Pharmacokinetics Model with Drug Dissolution Dynamics
Dae Shik Kim, Jong Hwan Sung, Jong Min Lee

12:52 PM

(494b) Discovery of Biomarkers Using High-Throughput Proteomics for Temporal Profiling of Periodontitis
Yannis A. Guzman, Dimitra Sakellari, Christodoulos A. Floudas

01:14 PM

(494c) Evaluation of Stoichiometric and 13C Metabolic Flux Analysis Methods for Determining Intracellular Fluxes in Mammalian Cells
Daniel Odenwelder, Sarah W. Harcum, Arthur Nathan Brodsky

01:36 PM

(494d) Modeling the Formation and Function of Responsive Peptide Systems
Ming-Chien Hsieh, Chenrui Chen, Junjun Tan, Tolu Omosun, Anil Mehta, David Lynn, Martha Grover

01:58 PM

(494e) Modulating Shear with a Population Balance Equation Model to Sustain Aggregate Size Distributions in Plant Cell Culture
Sarah A. Wilson, Shashank N. Maindarkar, Michael Vilkhovoy, Michael Henson, Susan C. Roberts

02:20 PM

(494f) Metabolic Model-Guided Glycoengineering in Escherichia coli
Joseph A. Wayman, Thomas J. Mansell, Matthew P. DeLisa, Jeffery D. Varner

02:42 PM

(494g) Computational and Experimental Modeling of Hyperthermia in Physiological Systems
Joel Coffel, Eric Nuxoll