2013 AIChE Annual Meeting

Session: Protein Engineering III: Therapeutics I

This session will focus on protein engineering for therapeutic applications, with an emphasis on emerging topics and recent successes. Potential areas of interest include, but are not limited to, (1) advances in protein-based therapeutics, (2) proteins for cell targeting and imaging, and (3) proteins involved in disease pathology.

Chair

Segatori, L., Rice University

Co-Chair

Chen, Y. Y., University of California - Los Angeles

Presentations

03:33 PM

(205b) Production of the Trimeric Influenza Hemagglutinin Stem Domain for Potentially Broadly Protective Influenza Vaccines
Lu, Y., Swartz, J. R.

03:51 PM

(205c) Logical Computation By Chimeric Antigen Receptors Increases Tumor-Targeting Capability of Engineered T Cells
Chen, Y.

04:09 PM

(205d) Engineered Mono-Specific Proteins As In Vivo Imaging Agents That Target Tumor Vasculature
Cochran, J. R., Silverman, A. P., Kapur, S., Cherf, G. M., Ye, A.

04:27 PM

(205e) Advances in Engineering a Human Cystathionine-?-Lyase for Systemic L?Methionine Depletion Cancer Therapy
Paley, O. M., Lu, W. C., Stone, E. M., Georgiou, G., Cheung, N. K., Hu, J.

04:45 PM

(205f) A Suite of Anti-Fibroblast Activation Protein-Alpha Antibodies for Targeting the Tumor Microenvironment
Van Deventer, J. A., Sidhu, S., Rajan, S., Wittrup, K. D.

05:03 PM

(205g) Engineering Ligand Biophysics to Enhance Tumor Targeting
Hackel, B. J., Case, B.

05:21 PM

(205h) Selective Inhibition of Weak-Affinity Epitope-IgE Interactions Via Heterobivalent Inhibitor Design Prevents Mast Cell Degranulation
Handlogten, M. W., Kiziltepe, T., Serezani, A., Kaplan, M., Bilgicer, B.