2013 AIChE Annual Meeting

Session: Poster Session: Pharmaceutical Engineering

Poster Session: Pharmaceutical Engineering

Chair

Otute Akiti, Relypsa

Co-Chair

Shailendra Bordewekar, Abbott Laboratories

Presentations

06:00 PM

(586y) Near-Infrared Spectroscopy for Predicting Dry Granulated Ribbon Density: Effect of Modeling Approach, Chemical Composition, and Spectroscopic Signature On Calibration Model's Performance
Sameer Talwar, Cletus Nunes, Timothy Stevens, Vishwas Nesarikar, Peter Timmins, Carl A. Anderson, James K. Drennen
(586u) Design of An Interface for Integrating PAT Tools in Continuous Manufacturing for in-Line Real Time Sensing
Abhishek Sahay, Eric Jayjock, Eric Sanchez, Fernando J. Muzzio, Rodolfo J. Romañach
(586ak) An Alternate Coating Method for Tablets: Wurster Technology
Howard Stamato, Steve Pafiakis, Rekha Keluskar, Christopher Levins, Kyle Martin, Shujie Lin, Wei Chen, John Fiske, Ravi Tejwani, Peter Timmins
(586z) Virtual High-Throughput Screening By Multi-Dimensional Characterization Techniques
Robert Herring, Mario Eden
(586p) Optimization of Protein Pegylation
Brandon Corbett, Xiaojiao Shang, Raja Ghosh, Prashant Mhaskar
(586am) Feasibility of Spray Dried Dispersion (SDD) Based Low Dose Tablet Formulation
Peter Ferrie, Cletus Nunes, Jay Poorna Reddy, Andrew Dennis, Elizabeth Banks, Patrick Wray, John Gamble, Howard Stamato, Peter Timmins
(586aa) Consistent Freezing of Bulk Protein Solutions - the Importance of Heat Flow Direction
Miguel A. Rodrigues, Monica Rosa, Singh K. Satish, Vitor Geraldes, Diana Gomes
(586b) Bioproduction and Formulation Patents - Opportunities and Challenges for Biotherapeutic Development
Paul Calvo
(586c) Selection of Polymorphic Forms Via Continuous Kinetically Controlled Msmpr Crystallization
Steven T. Ferguson, Tsai-Ta Chris Lai, Laura Palmer, Bernhardt L. Trout, Allan S. Myerson
(586v) An Effective and Facility Compatible Cleaning in Place (CIP) Procedure for Affinity Resin in Monoclonal Antibody (Mab) Purification
Lu Wang, Jill Dembecki, Neil Jaffe, Hui Cai, Colleen Sparks, Jian Zhang, Sarah Laino, Reb Russell, Michelle Wang
(586w) Assessing the Relative Cleanabilities of Bioprocess Soils
Joseph Wood, Adeyma Arroyo
(586r) Simulation and Global Sensitivity Analysis of Pharmaceutical Processes for Solid Drug Manufacture
Amanda Rogers, Marianthi Ierapetritou, Chaitali Inamdar
(586e) Control Strategy Development for QbD Submission
Sze Wing (Candice) Wong, Utpal Singh, Michael Kopach, Christa Mulkey
(586a) Development and Evaluation of Nanostructured Formulations Containing 8-Methoxalen
Thais Barradas, Claudia E. Mansur, K. Gyselle Silva, Ana Paula de Sá Pinto
(586ab) An In-Silico Approach for Investigating Molecular Interactions in Carbohydrate-Water Mixtures
Jasmine Gupta, Cletus Nunes, Sriramakamal Jonnalagadda
(586ac) Effect of Plasticizer On Glass Transition Temperature of Amorphous Pharmaceuticals - A Computational Study
Jasmine Gupta, Cletus Nunes, Sriramakamal Jonnalagadda
(586f) Using On-Line Mass Spectrometry to Predict the End Point During Drying of Pharmaceutical Products
Aditya G. Dodda, Michael A. Henson, Kostas Saranteas
(586ad) Effect of Double Layer Formulation On Crystallization of Naproxen/Polyethylene Glycol Dispersion System
Hsin-Yun Hsu
(586g) Process Optimisation of Chromatography Units Using First Principles Modelling Techniques
Amy J Green, Elaine Martin, Graham McCreath
(586ae) Disposable Bags in Biopharmaceutical: Approaches to Storing Difficult Solutions
Kate Lee, Adeyma Arroyo, Ekta Mahajan
(586h) Operational Aspects Of Continuous Pharmaceutical Production
Aleksandar Mitic, Krist V. Gernaey, Kim Dam Johansen, Tommy Skovby
(586i) Optimal Antisolvent Addition Profile in a Continuous Plug Flow Crystallizer Through Population Balance Based Multi-Objective Optimization
Aniruddha Majumder, Bradley J. Ridder, Zoltan K. Nagy
(586j) Dynamic Modeling of Encrustation and Mitigation Strategies in a Continuous Plug Flow Crystallizer
Zoltan K. Nagy, Aniruddha Majumder
(586k) Chemoenzymatic Synthesis of Heparin for a Safer Bioengineered Alternative
Ujjwal Bhaskar, Bo Yang, Li Fu, Majde Takieddin, Fuming Zhang, Shaker A. Mousa, Jian Liu, Jonathan Dordick, Robert J. Linhardt
(586l) Implementation of a Novel Inline Particle Size Measurement Tool to Monitor Pellets Produced By Hot Melt Extrusion and Die Face Pelletizing
Daniel Treffer, Patrick Wahl, Theresa Hörmann, Daniel Markl, Andreas Eitzlmayr, Simone Schrank, Gerold Koscher, Eva Roblegg, Johannes G. Khinast
(586s) Characterization of Solid-State Forms and Phase Transformations of Clindamycin Phosphate
Ranyuan RAN
(586af) Model Based Robustness Analysis of An Industrial Ion Exchange Step
Thomas B Hansen, Ernst B. Hansen
(586ag) Evaluation of Film Coated Tablet Surface Roughness Via a Latent Variable Design-of-Experiments (DOE)
James E. Miesle, Leo Manley
(586n) In-Line Monitoring of a Fluid-Bed Coating Process With Optical Coherence Tomography
Stephan Sacher, Daniel Markl, Günther Hannesschläger, Michael Leitner, Johannes G. Khinast
(586ah) Novel Approach for Stabilizing Physical Form of a Drug Substance in Tablet Formulations
Cletus Nunes, Dilbir Bindra, Madhushree Gokhale, Ajit Thakur
(586o) Design of An Efficient Control System for Flexible Continuous Tablet Manufacturing Process
Ravendra Singh, Abhisheck Sahay, Marianthi Ierapetritou, Rohit Ramachandran
(586ai) Scale Up of the Chromatographic Process
Steffen Kidal, Ernst B. Hansen
(586aj) Development of a Robust Film Coating Process: The Impact of Wetting Dynamics On the Film Stress - Film Adhesion Balance
Jennifer (Ho) Sun, Joanne Lu, Stephen L. Conway, Eric Seymour, W. Mark Eickhoff
(586t) Continuous Direct Compaction As a Manufacturing Route for Highly Segregating Blends
Sarang Oka, Abhishek Sahay, Fernando Muzzio