2013 AIChE Annual Meeting

Session: Nucleic Acid Delivery

This session seeks to explore topics associated with the development of novel gene delivery vehicles and processes in gene and/or oligonucleotide delivery.

Chair

Ramsey, J., Oklahoma State University

Co-Chair

Jewell, C., University of Maryland

Presentations

03:15 PM

(560a) Polymer-Based Multilayer Coatings for the Rapid Release of DNA From Surfaces: A Weak Polyelectrolyte Approach
Yu, Y., Lynn, D., Bechler, S. L., Si, Y., Liu, B.

03:33 PM

(560b) Synergistic Combination of Coated Microneedles and Biochemical Approaches for Oligonucleotide Delivery to Cells in 3D Tissues
Gill, H. S., Nitin, N., Luo, Z., Ye, T., Ma, Y.

03:51 PM

(560c) Cellular and Molecular Factors Contribute to An in Vitro Refractory Period Between Sequential DNA Complex Deliveries
Kelly, A. M., Martin, T. M., Plautz, S. A., Pannier, A. K.

04:09 PM

(560d) Acid-Degradable Polyketal Nanoparticles Carrying MnSOD siRNA to Restore Intrinsic Apoptosis in Tamoxifen-Resistant Breast Cancer Cells
Kwon, Y. J., Cho, S. K., Kemp, J. A., Pedram, A., Levin, E. R.

04:27 PM

(560e) Dendrimer-siRNA Complexes and Their Aerosol Formulation for Lung Delivery Applications
Conti, D. S., Brewer, D., Grashik, J., Avasarala, S., da Rocha, S. R. P.

04:45 PM

(560f) Modification of Fiberless Adenovirus With a Polymer/Peptide Conjugate for Enhanced Transduction and Reduced Immune Response
Ramsey, J. D., Nigatu, A., Kupgan, G.

05:03 PM

(560g) In Vivo Evaluation of AAV-Mediated Gene Transfer in Airways of Mice With Acute Or Chronic Respiratory Infection
Myint, M., Limberis, M. P., Diamond, S. L.

05:21 PM

(560h) Directed Evolution of Adeno-Associated Virus for Enhanced Evasion of Human Neutralizing Antibodies
Kotterman, M. A., Hwang, B. Y., Stone, D., Koerber, J. T., Couto, L., Mingozzi, F., High, K., Schaffer, D. V.