2013 AIChE Annual Meeting

Session: Nucleic Acid Delivery

This session seeks to explore topics associated with the development of novel gene delivery vehicles and processes in gene and/or oligonucleotide delivery.

Chair

Joshua Ramsey, Oklahoma State University

Co-Chair

Christopher Jewell, University of Maryland

Presentations

03:15 PM

(560a) Polymer-Based Multilayer Coatings for the Rapid Release of DNA From Surfaces: A Weak Polyelectrolyte Approach
Yan Yu, David Lynn, Shane L. Bechler, Yi Si, Bo Liu

03:33 PM

(560b) Synergistic Combination of Coated Microneedles and Biochemical Approaches for Oligonucleotide Delivery to Cells in 3D Tissues
Harvinder S. Gill, Nitin Nitin, Zhen Luo, Ting Ye, Yunzhe Ma

03:51 PM

(560c) Cellular and Molecular Factors Contribute to An in Vitro Refractory Period Between Sequential DNA Complex Deliveries
Abby M. Kelly, Timothy M. Martin, Sarah A. Plautz, Angela K. Pannier

04:09 PM

(560d) Acid-Degradable Polyketal Nanoparticles Carrying MnSOD siRNA to Restore Intrinsic Apoptosis in Tamoxifen-Resistant Breast Cancer Cells
Young Jik Kwon, Soo Kyung Cho, Jessica A. Kemp, Ali Pedram, Ellis R. Levin

04:27 PM

(560e) Dendrimer-siRNA Complexes and Their Aerosol Formulation for Lung Delivery Applications
Denise S. Conti, Daniel Brewer, Jordan Grashik, Sumant Avasarala, Sandro R. P. da Rocha

04:45 PM

(560f) Modification of Fiberless Adenovirus With a Polymer/Peptide Conjugate for Enhanced Transduction and Reduced Immune Response
Joshua D. Ramsey, Adane Nigatu, Grit Kupgan

05:03 PM

(560g) In Vivo Evaluation of AAV-Mediated Gene Transfer in Airways of Mice With Acute Or Chronic Respiratory Infection
Melissa Myint, Maria P. Limberis, Scott L. Diamond

05:21 PM

(560h) Directed Evolution of Adeno-Associated Virus for Enhanced Evasion of Human Neutralizing Antibodies
Melissa A. Kotterman, Bum-Yeol Hwang, Daniel Stone, James T. Koerber, Linda Couto, Federico Mingozzi, Katherine High, David V. Schaffer