2013 AIChE Annual Meeting

Session: Industrial Forum: Innovations in Biopharmaceutical Discovery, Development and Manufacturing

This session will highlight recent innovations and advancements in biopharmaceutical discovery, development and manufacturing strategies. Technologies that accelerate biotech therapy development or facilitate more flexible, lower cost manufacturing will be included in this session.

Chair

Gregory Frank, Amgen Inc.

Co-Chairs

Bruno F. Marques, GlaxoSmithKline
Ruta Waghmare, EMD Millipore

Presentations

03:15 PM

(548a) Improvement of Cell-Freezing Technologies and Disposable Bioreactors: Toward a Fully Closed USP Process?
Sebastien Ribault

03:40 PM

(548b) Effect of Anti-Apoptosis Genes On Clarification Performance
Ajish Potty, Anthony DiLeo, Alex Xenopoulos

04:05 PM

(548c) Process Development Comparison of Single Use Clarification Technologies for Mammalian Cell Cultures Utilizing a Conventional Two-Stage Depth Filtration, a New Optimized Depth Filter and a Novel Single-Use Fluidized Bed Centrifuge With Depth Filtration
Juan C. Castano, Matthew M. Westoby, Sanaa Elouafiq, Devin McCann

04:30 PM

(548d) Impurity Removal in a Mab Process Using Depth Filtration Following Protein A
John Schreffler, Matt Bailley, Erick Wiltsie, Tom Klimek

04:55 PM

(548e) Integrated Reaction Modeling and Process Evaluation in the Development of Bioconjugation Technology Platform
Sa V. Ho, John J Buckley, Sydney Hoeltzli, Chandra Gamlath, Mark Pozzo

05:20 PM

(548f) Implementing a Flexible Recipe Management Strategy for Development of Biopharmaceuticals
Alison Harkins, Adam Fermier, Richard Yeager