2013 AIChE Annual Meeting

Session: Applications of Continuous Processing in the Manufacture of Pharmaceuticals: Drug Substance

Applications of Continuous Processing in the Manufacture of Pharmaceuticals: Drug Substance

Chair

Shailendra Bordewekar, Abbott Laboratories

Co-Chair

Jacob Albrecht, Bristol-Myers Squibb

Presentations

12:30 PM

(466a) A Continuous Flow Grignard At Scale
Sylvia O. Nwosu, Martin Johnson, Kevin Seibert, Michael Kopach, Timothy M. Braden, Mark S. Kerr, Jonathan J. Adler, John P. Schafer

12:55 PM

(466b) Packed-Bed Hydrogenolysis: A Multi-Scale Study
Nikolay Zaborenko, Ryan J. Linder, Bradley M. Campbell

01:20 PM

(466c) Design and Scale-Up of the Continuous Reactive Crystallization of An API
Christopher S. Polster

01:45 PM

(466d) Use of Continuous Msmpr Crystallization With Integrated Nanofiltration Membrane Recycle for Enhanced Yield and Purity in API Crystallization
Steven T. Ferguson, Franziska Ortner, Justin Quon, Ludmila G. Peeva, Andrew Livingston, Allan S. Myerson, Bernhardt L. Trout

02:10 PM

(466e) Model-Predictive Control Strategies for Improved Bioprocess Performance
Brian Glennon, Jessica Whelan, Mark Barrett

02:35 PM

(466f) Small Scale Media Optimization for Continuous Culture – Effect On Cellular Metabolism
Daniel Karst, Massimo Morbidelli, Miroslav Soos