2012 AIChE Annual Meeting

Session: Scale-up of Pharmaceutical Manufacturing Processes - A QbD Approach

Co-Chair

James Marek, Abbott Laboratories

Presentations

12:30 PM

(310a) Optimal Design of Transient Microreactor Experiments

12:55 PM

(310b) Building Process Robustness and Flexibility Through Implementation of QbD Methodologies
Kevin Sirk, Luke Schenck, Paul Fernandez, Lorrie Berwick, Rositza Petrova, Jason Dorwart

01:20 PM

(310c) Scale-up Considerations for a Continuous Process with QbD in a Manufacturing Setting
Stephen B. Jeffery

01:45 PM

(310d) Application of the Discrete Element Method (DEM) to Understand a Powder Blending Process and De-Risk Scale-up
Patrick Daugherity

02:10 PM

(310e) Validation of a Scale-up Model for the Lubrication Blending Process From Material Sparing to Commercial Scale
Joseph Kushner, Margit Karle, Holger Schlack, Deborah Booth-Schindler

02:35 PM

(310f) Quality by Design Development of a Film Coating Process Resulting in a Dimensionless Design Space
Fochive N. Njikam, Manoharan Ramasamy