2011 Annual Meeting

Session: Scale-up of Pharmaceutical Isolation and Drying Operations

Chair

Saravanababu Murugesan, Bristol-Myers Squibb Co

Co-Chair

David Lamberto, Merck & Co., Inc.

Presentations

12:30 PM

(120a) A Combined Experimental and Model-Based Approach to Prediction of Particle Size Attrition In Agitated Dryers
Ann M. Czyzewski, Raimundo Ho, Carlos Orihuela, Ahmad Sheikh, Thomas B. Borchardt, Shailendra V. Bordawekar

12:50 PM

(120b) Investigation of Acoustic Dryer for API Processing
David Lamberto, Peter Lucon, Dwynn R. Nyquist, Josh E. Yarrington

01:10 PM

(120c) Near-Infrared Spectroscopy for On-Line Drying End-Point Determination In a Small-Scale Fluidized Bed
Nicolas Heigl, Johannes G. Khinast, Benjamin Glasser, Fernando J. Muzzio

01:30 PM

(120d) Developing a Robust Isolation and Drying Protocol for An API with Unique Physical Properties
Amanda Rogers, Saravanababu Murugesan, Alan Braem, William Bartels, Jose Tabora

01:50 PM

(120e) Developing Dynamic Models of Pharmaceutical Drying Operations Using On-Line Mass Spectroscopy
Aditya Gopi

02:10 PM

(120f) Development of Laboratory Methods (“Predictive Tools”) to Preserve Particle Properties of APIs Upon Scale-up to Agitated Filter Driers
David J. am Ende, Mark T. Maloney, Steven J. Brenek, Brent Maranzano