2011 Annual Meeting

(623o) Supercooling: An Alternative Biopreservation Scheme

Authors

Basak Uygun - Presenter, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospital for Children
Korkut Uygun - Presenter, MGH/Harvard Medical School
Yeonhee Kim - Presenter, Virginia Polytechnic Institute and State University


The objective of this study is to extend the viable preservation time of hepatic tissues by sub-zero non-freezing (SZNF) storage in a supercooled preservation medium. The hypothesis here is that the preserved liver viability is correlated strongly to metabolic activity. In this session I will discuss our efforts on this alternative preservation scheme with results from both in-vitro and invivo studies.