2010 Annual Meeting

Session: Protein Engineering I - Therapeutics

This session will focus on protein engineering for therapeutic applications with an emphasis on emerging topics and recent successes. Possible areas of interest include, but are not limited to, (1) advances in protein-based therapeutics, (2) proteins for cellular targeting and imaging, abd (3) proteins involved in disease pathology.

Chair

Jennifer A. Maynard, University of Texas at Austin

Co-Chair

Brad Bundy, Brigham Young University

Presentations

08:30 AM

(47a) De Novo Computational Design of Nanobodies and Scfvs
Robert J. Pantazes, Costas D. Maranas

08:50 AM

(47b) Novel Technologies for the Detection of Alpha-Synuclein Misfolded Toxic Species
Ahmed M. Kothawala, Laura Segatori

09:10 AM

(47c) Calcium Channel Blockers Can Attenuate Amyloid-Beta Self-Assembly: Potential as Dual-Action Drug for Alzheimer's Disease
Jui-Heng Tseng, Sukhi K. Guram, Melissa A. Moss

09:30 AM

(47d) Engineered Bispecific Proteins That Simultaneously Bind to and Inhibit Both VEGFR2 and Alphav Beta3 Integrin for Cancer Therapy and Diagnosis
Jennifer R. Cochran, Adam P. Silverman, Niv Papo

09:50 AM

Intermission

10:00 AM

(47e) Genetically Engineered Alginate Lyase for the Treatment of Bacterial Biofilms
John W. Lamppa, Karl E. Griswold, Thomas C. Scanlon, Margaret E. Ackerman, Jennifer Lai

10:20 AM

(47f) Mucosal Immunization Utilizing An Engineered Targeting Ligand
Tarik A. Khan, Jennifer A. Maynard

10:40 AM

(47g) An Influenza A/H1N1/2009 Hemagglutinin Vaccine Produced in Escherichia Coli
Mario M. Alvarez, J. Manuel Aguilar-Yáñez, David Bulnes-Abundis, Roberto Portillo-Lara, Sergio García-Echauri, Gonzalo Ismael Mendoza-Ochoa, Felipe López-Pacheco, Stephen White, Rebecca María Dubois, Charles Russell, Stacey Schultz-Cherry