2009 Annual Meeting

Session: Scale-up Issues in Bio/Pharmaceutical Process Development

Chair

Elizabeth Spiteri, Bristol-Myers Squibb Company

Co-Chairs

Pavol Rajniak, Merck &Co.
Kumar M. Dhanasekharan, Genzyme Corporation

Presentations

12:30 PM

(430a) Optimization of Monoclonal Antibody Production Using Process Simulation and Production Scheduling Tools
Charles Siletti, Demetri Petrides

12:50 PM

(430b) Safe Practices for Azide Chemistry Scale-up: A Case Study On a Pharmaceutical Intermediate
Nathaniel Kopp, Francisco González-Bobes, Joerg Deerberg, Michael Hrytsak, Simon Leung, Praveen Sharma

01:10 PM

(430c) Modeling of Cake Filtration – Applications in Predicting the On-Scale Filtration Performance of Various Pharmaceutical Intermediates
Saravanababu Murugesan, Jose Tabora, Peter Clark, Daniel Hallow, James Vernille

01:30 PM

(430d) Control of Deamidation of Monoclonal Antibodies in Mammalian Cell Culture Processes
John C. Chen, Thoa Bui, Vaibhav Hegde, Saravanamoorthy Rajendran, Dhara Mandavia, Methal Albarghouti

02:00 PM

(430e) Impact of Scale On Wet Mill Performance
Deniz Erdemir, Aghogho Pedro, Kavita Vemishetti

02:20 PM

(430f) Qualification of a Scale Down Cell Culture Model for Process Characterization Studies
Lia Tescione, James Lambropoulos, Ram Paranandi, Helena Yusuf-Makagiansar