2008 Annual Meeting

Session: Mathematical Approaches in Systems Biology

This session is devoted to theoretical and computational studies of biological systems. Such systems include protein/DNA interactions, protein/protein interactions, genetic networks, metabolic pathways, and signal transduction pathways. Presentations will focus on theoretical and computational developments for the study of the behavior of these systems in response to stimulation or changes in their kinetic and thermodynamic properties. Contributions of novel computational strategies for systems biology are especially welcome.

Chair

Rajanikanth Vadigepalli, Thomas Jefferson University

Co-Chair

Juergen Hahn, Dept. of Chemical Engineering, Texas A&M University

Presentations

03:15 PM

(698a) De Novo Protein Design Based on Binding Affinity Predictions for the Discovery of Novel Inhibitors for Complement 3 and HIV-1
Meghan L. Bellows, Hoki Fung, Christodoulos A. Floudas

03:35 PM

(698b) Quantitative Measurement Technique for Transcription Factor Profiles
Zuyi (Jacky) Huang, Fatih Senocak, Arul Jayaraman, Juergen Hahn

03:55 PM

(698c) Reconstructing Transcription Factor Networks Using the Living Cell Array
Eric Yang, Ioannis Androulakis, Martin Yarmush

04:15 PM

(698d) Single-Cell Behavior and Population Heterogeneity: An Inverse Modeling Approach for Computing the Intrinsic Physiological State Functions
Konstantinos Spetsieris, Nikos V. Mantzaris, Kyriacos Zygourakis

04:45 PM

(698e) Stochastic Simulation and Systems Analysis of Insulin-Stimulated GLUT4 Translocation
Eric C. Kwei, Kevin R. Sanft, Jason E. Shoemaker, Linda R. Petzold, Francis J. Doyle

05:05 PM

(698f) Small World Network Models of Intercellular Coupling In the Mammalian Circadian Clock
Christina Vasalou, Mark Freeman, Erik D. Herzog, Michael A. Henson