2008 Annual Meeting

Session: Biomaterials for Gene Delivery

This sessions discusses the delivery of viral and non-viral gene therapy vectors using biomaterials to overcome one or more of the barriers to delivery. Note: Oral presentations will be reserved primarily for abstracts where gene transfer is demonstrated.

Chair

Co-Chair

Angela K. Pannier, University of Nebraska-Lincoln

Presentations

12:30 PM

(70a) Targeted, Endosomolytic Polymer Delivery Vehicles for siRNA
Danielle Benoit, Craig L. Duvall, Anthony J. Convertine, Allan S. Hoffman, Patrick S. Stayton

12:49 PM

(70b) Novel Graft Copolymers Enhance Cationic Lipid Mediated Delivery of Oligonucleotides
Lavanya Peddada, Nicole Harris, David Devore, Charles M. Roth

01:08 PM

(70c) Local Gene Delivery from Ecm Coated Poly (lactide co glycolide) Multiple Channel Bridges after Spinal Cord Injury
Laura De Laporte, Anna Yan, Lonnie D. Shea

01:27 PM

(70d) Target Cell Controlled and Spatially Arranged Gene Delivery from Fibrin Hydrogels
Pedro Lei, Roshan Padmashali, Stelios T. Andreadis

01:46 PM

(70e) DNA Delivery from Enzymatically Degradable Synthetic Hydrogels to Invading Cells Results In Sustained Transgene Expression
Yuguo Lei, Tatiana Segura

02:05 PM

(70f) Targeting of Polymer Gene Carriers Increases Uptake in Cells but Reduces DNA Release and Overall Expression Efficiency
Yen Cu, Michael J. Caplan, W. Mark Saltzman

02:24 PM

(70g) Intracellular Trafficking of Pentablock Copolymer/ DNA Polyplexes In Cultured Human Cancer and Normal Cells for Gene Delivery
Bingqi Zhang, Surya K. Mallapragada

02:43 PM

(70h) Novel pH-Triggered Nanoparticles for Gene Delivery Have High Transfection and Low Cytotoxicity
Jin-Oh You, Debra. T Auguste