2006 AIChE Annual Meeting

Session: Separations in Biopharmaceutical Downstream Processing I

The focus of this session will be the downstream separation processes such as MF/UF, chromatography (ion exchange, reverse phase, size exclusion, affinity), crystallization, etc.

Chair

Co-Chair

Menkhaus, T. J., South Dakota School of Mines and Technology

Presentations

12:30 PM

(410a) Comparison of a New Continuous Chromatographic Solvent Gradient Process for Bioseparations with Conventional Processes
Stroehlein, G., Aumann, L., Tarafder, A., Mueller-Spaeth, T., Morbidelli, M.

12:50 PM

(410b) Scale down Model Demonstrates High Prodcut Throughputs with Disposable Anion Exchange Chromatography
Mora, J. D., Gottschalk, U., Reif, O., Zhou, J., Solamo, F., Dermawan, S., Hong, Y., Tressel, T.

01:10 PM

(410c) Downstream Separation and Scale-up Challenges for E.Coli-Derived Biopharmaceuticals – an Industrial Study on Development of an Antibody Fragment (Fab) Process
Wajid, A., Narindray, D.

01:30 PM

(410d) A Toolbox for Efficient Release and Recovery of Therapeutic Proteins from the Periplasm of Pseudomonas Fluorescens
Patkar, A., Sen, S., Chappell, M., Chiu, Y., Allen, J., Shields, J.

01:50 PM

(410e) Diverse Transgenic Plant Hosts Challenge Downstream Process Development
Nikolov, Z. L., Woodard, S. L., Wilken, L. R., White, S. G., Barros, G.

02:10 PM

(410f) High Throughput Protein Purification Using Negative Mode Hydrophobic Interaction Chromatography
McNay, J., Audo, K., Bailey, K.

02:30 PM

(410g) Separation of Pharmaceutical Process-Related Impurities by an Organic Solvent Nanofiltration Membrane Cascade
Lin, J. C. T., Peeva, L. G., Livingston, A. G.