2006 AIChE Annual Meeting

Session: Separations in Biopharmaceutical Downstream Processing I

The focus of this session will be the downstream separation processes such as MF/UF, chromatography (ion exchange, reverse phase, size exclusion, affinity), crystallization, etc.

Chair

Co-Chair

Todd J. Menkhaus, South Dakota School of Mines and Technology

Presentations

12:30 PM

(410a) Comparison of a New Continuous Chromatographic Solvent Gradient Process for Bioseparations with Conventional Processes
Guido Stroehlein, Lars Aumann, Abhijit Tarafder, Thomas Mueller-Spaeth, Massimo Morbidelli

12:50 PM

(410b) Scale down Model Demonstrates High Prodcut Throughputs with Disposable Anion Exchange Chromatography
Jeff D. Mora, Uwe Gottschalk, Oscar Reif, Joe Zhou, Felix Solamo, Shinta Dermawan, Yongsuk Hong, Tim Tressel

01:10 PM

(410c) Downstream Separation and Scale-up Challenges for E.Coli-Derived Biopharmaceuticals – an Industrial Study on Development of an Antibody Fragment (Fab) Process
Abdul Wajid, Daljit Narindray

01:30 PM

(410d) A Toolbox for Efficient Release and Recovery of Therapeutic Proteins from the Periplasm of Pseudomonas Fluorescens
Anant Patkar, Subrata Sen, Mike Chappell, Yuk Chiu, Jeff Allen, Jefry Shields

01:50 PM

(410e) Diverse Transgenic Plant Hosts Challenge Downstream Process Development
Zivko L. Nikolov, Susan L. Woodard, Lisa R. Wilken, Steve G. White, Georgia Barros

02:10 PM

(410f) High Throughput Protein Purification Using Negative Mode Hydrophobic Interaction Chromatography
Jennifer McNay, Kenneth Audo, Kevin Bailey

02:30 PM

(410g) Separation of Pharmaceutical Process-Related Impurities by an Organic Solvent Nanofiltration Membrane Cascade
Justin Chun-Te Lin, Ludmila G. Peeva, Andrew G. Livingston