2006 AIChE Annual Meeting

Session: Process Development Tools for Pharmaceutical Process Development

The pharmaceutical engineering lab is endowed with on-line probes that hold the promise of rapid process development without sacrificing process understanding. This session will focus on the application of these lab tools in solving process problems.

Chair

Shailendra V. Bordawekar, Abbott Laboratories

Co-Chair

Brent Nielsen, Bristol-Myers Squibb Company

Presentations

08:30 AM

(641a) Shear-Induced Compaction of Pharmaceutical Formulations

Marcos Llusa, Bodhisattwa Chaudhuri, M. Silvina Tomassone, Abdul M. Faqih, Amit Mehrotra, Fernando J. Muzzio

08:51 AM

(641b) A Numerical Investigation of Air Flow during Tablet Compression

Douglas M. Kremer

09:12 AM

(641c) Combined Experimental and Modeling Study of a Kinetic Resolution

John W. Shabaker, Srinivas Tummala, Erqing Tang, Olav Lyngberg, Lindsay Hobson

09:33 AM

(641d) On-Line Ftir Measurements for the Pilot-Plant Scale-up of a Borane Reduction Process

Camille O. Anderson, George Zhou, Brian Phenix

09:54 AM

(641e) Development of a Generic Process Model for Dynamic Simulation of Protein Downstream Processes

Constantin Frerick, Peter Kreis, Andrzej Górak

10:15 AM

(641f) Catalyst Trap Microreactor for Pharmaceutical Hydrogenation

Shaun M. McGovern, G. Harish, Ronald S. Besser

10:36 AM

(641g) Ion Exchange Process Development with Pat

James Marek, Shekhar K. Viswanath, John Tolle