Protein degradation occurs throughout the life cycle of biotechnology products, and can involve a variety of physical and chemical routes. This session seeks contributions that focus at a fundamental level on the mechanism(s), kinetics, and/or quantitative modeling of one or more degradation pathways for proteins in vitro or in vivo. These may include, but are not limited to: deamidation, oxidation, proteolysis, and non-native aggregation. Priority will be given to those contributions that provide insights or applications of general use, and those that apply modern computational or theoretical tools.
08:30 AM
Jason K. Cheung, Vincent K. Shen, Jeffrey Errington, Thomas Truskett
08:55 AM
Victoria Wagoner, Carol K. Hall
09:20 AM
Jindal K. Shah, Dilip Asthagiri, Michael E. Paulaitis
09:45 AM
James M. Broering, Andreas S. Bommarius
10:10 AM
Jennifer Andrews, Christopher J. Roberts
10:35 AM
Hung Nguyen, Charles L. Brooks