2006 AIChE Annual Meeting

(369e) Is It Del B, or Del B^2? That Is the Question

Authors

Chalmers, J. J. - Presenter, The Ohio State University
Zborowski, M., Cleveland Clinic Foundation
Sun, J., The Ohio State University
Zhao, Y., The Ohio State University
The Zborowski and Chalmers lab have been advocating the use of magnetophoretic mobility as a means to both characterize the degree to which a cell is immunomagnetic labeled as well as a means to design, operate, and analyze the performance of immunmagnetic cell separation systems. A common criticism/concern of our method of calculating magnetophoretic mobility is the use of the magnetic energy gradient calculated as Del B^2 instead of Del B.

In this presentation we will present our experimental studies with our modified electromagnetic CTV system which allows us to vary the value of B over and order of magnitude. This allows for the direct answering of the question: Is the magnetophoretic mobility constant as Del B^2 changes? We will present experimental evidence that based on the material and value of B, both sides in the debate are correct.