2005 Annual Meeting

(488c) Determining the Effect of Cytoskeleton Disruption on Cell Rheology

Authors

Kathleen Miranda - Presenter, University of Pennsylvania
Brenton D. Hoffman - Presenter, University of Pennsylvania
Gladys Massiera - Presenter, Laboratoire de Spectometrie Physique
John Crocker - Presenter, University of Pennsylvania


Understanding cell mechanics is a prerequisite for a detailed understanding of mechano-transduction, which is involved in numerous biological processes such as cell motility and differentiation. Previous studies have shown cells exhibit a power law shear modulus over several decades. The rheology (G ~ ωβ) varies between 0.1